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As the Obamas time in the White House draws to a close, all eyes are narrowing in on the last few official events the President and First Lady will attend

Hundreds of dissimilar scientific works have been published proposing countless treatments for DS, the main therapeutic categories include natural products, chemical compounds, physical methods, anesthetics, bioactive substances and commercial preparations [7][25] (Table I) which has caused great confusion in the therapies applied by dentists and controversies in the scientific field

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